Crank is a "18" rated blur as set by the official BBFC coordinators. It revolves about Carlito (Carlos Sanz), who leads a affluent and affecting Mexican-American abomination syndicate in Los Angeles, he artlessly referred to in the blur as the "West Coast Abomination Syndicate". Worried about the assailment of a accumulation into LA of heavily-armed associates of the Chinese mafia, and the furnishings that may accept aloft his operations, Carlito orders the arrangement killing of their leader, Don Kim (Keone Young). Carlito's best hitman, an English man alleged Chev Chelios (Jason Statham), is ordered to do the job. However Carlito has underestimated the Chinese and afterwards the hit, the calefaction from Hong Kong is abundant greater than Carlito expected. Carlito anon abjure that the hit may accept been "ill-advised" and to affluence the burden Carlito offers the Chinese both an account and a solution: the hit was annihilation to do with him, and Carlito will himself abolish assertive elements aural his own alignment who were amenable and operating on their own.
Ricky Verona (Jose Pablo Cantillo), a baby time jailbait and adept battling of Chev Chelios, uses the befalling to cabal with Carlito adjoin Chelios, unbeknown to Chelios who believes Carlito is still loyal to him. While Chelios sleeps in his accommodation one night, Verona silently break in and injects Chelios with the "Beijing Cocktail". This is a constructed biologic which inhibits the breeze of adrenaline from the adrenal glands, slowing the heart, and eventually killing the victim. Chelios wakes to acquisition a recorded video fabricated by Verona biting Chelios and answer the situation, and that Chelios should alone accept about an hour larboard afore the adulteration stops his heart.
Chelios speaks with an underground doctor who generally works as a claimed physician to the Mafia, Doc Miles (Dwight Yoakam), who informs Chelios while actuality massaged by a breast naked bikini babe in Las Vegas, that in adjustment to survive and accumulate his affection assault he charge accumulate his adrenaline pumping through connected action and danger, or get some bogus adrenaline, epinephrine (it should be acclaimed adrenaline is the aforementioned affair as epinephrine.) With his own adrenaline befitting the adulteration at bay at first, Chelios break into a hospital and steals abundant drugs, abundant added than Doc Miles advises him to booty and additionally actuality "juiced" by hits from a defibrilator. Even still he charge accumulate his adrenaline up through adventuresome and alarming acts such as acrimonious fights with added gangsters, burglary things, committing robberies, angry with badge and active cars through arcade malls.
The absolute blur takes abode over a distinct day, starting in the morning and activity through to backward afternoon/early evening. Over the advance of the day Chelios sets out to get his animus on Verona, alive that he apparently will not accomplish it to the end of the day, and attempting to acquisition Verona and his artery assemblage through Chelios' artery acquaintance Kaylo (Efren Ramirez), a baroque homosexual. Chelios additionally goes to aces up his backward adherent Eve (Amy Smart) afore Verona's thugs get to her. In one notable arena Chelios has sex with Eve in the average of a active artery in Chinatown while hundreds of bodies attending on, in adjustment to accumulate his adrenaline up.
In the end it is appear that Chelios never absolutely dead Don Kim, in actuality sparing his activity and cogent him to leave LA instead. Towards the end of the movie, Chelios arranges a auberge rooftop affair with Carlito, Verona and their henchman, who affiance him the (fake) antitoxin to the Beijing Cocktail. Don Kim arrives forth with his Triads to abetment Chelios, and in a abandoned shootout abounding of Carlito's men are killed. Carlito is dead by none added than an aggressive and betraying Verona, who again attempts to leave in Carlito's escape helicopter. The cine concludes with Chelios against Verona in the helicopter and as they action the brace abatement from the chopper bags of anxiety aloft LA, and mid-flight Chelios break Verona's neck, quipping "I told you I'd annihilate you, you little bitch!" He again calls Eve on his corpuscle phone, answer that he will not be advancing aback to her. Chelios hits a car, bounces off it and acreage appropriate in advanced of the camera. In the aftermost attempt it is adumbrated that his adrenaline is absolutely still abounding fast; his adenoids flare, he blinks, and two heartbeats are heard.
Main article: List of Crank characters
* Jason Statham as Chev Chelios/Crank
* Amy Smart as Eve Lydon
* Jose Pablo Cantillo as Ricky Verona
* Efren Ramirez as Kaylo
* Dwight Yoakam as Doc Miles
* Carlos Sanz as Carlito
* Keone Young as Don Kim
* Reno Wilson as Orlando
* Jay Xcala as Alex Verona
* Edi Gathegi as Haitian cab driver
* Chester Bennington (of Linkin Park) as Pharmacy customer/Adrenaline junkie
* Valarie Rae Miller as Chocolate
* Glenn Howerton as Male nurse
* Noel Gugliemi as Warehouse Rooftop Hood
* Francis Capra as Warehouse Hood Leader
* Candice A. Buenrostro as Bikini Girl